Ammonia → 5-(Pyridazin-4-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole

참여 물질

역할	이름	HCID	투입량
반응물	Ammonia	HCID 222	—
반응물	N-Hydroxynicotinimidamide	HCID 308113	—
반응물	Pyridazine-4-carboxylic Acid	HCID 2761046	—
생성물	5-(Pyridazin-4-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole	HCID 44544669	—

반응 단계

The titled compound was prepared according to the procedure of Method C using N′-hydroxynicotinimidamide (Aldrich) and pyridazine-4-carboxylic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.67 (ddd, J=8.1, 5.0, 0.8 Hz, 1H), 8.45 (dd, J=5.4, 2.4 Hz, 1H), 8.60 (dt, J=8.1, 1.9 Hz, 1H), 8.78 (dd, J=5.1, 1.7 Hz, 1H), 9.34 (dd, J=2.2, 0.8 Hz, 1H), 9.55 (dd, J=5.4, 1.4 Hz, 1H), 9.94 (dd, J=2.2, 1.2 Hz, 1H) ppm; MS (DCI/NH3) m/z=226 (M+H)+.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US09040568B2
출처 데이터셋	uspto-grants-2015_05
ORD ID	ord-cf90ee90b9be4c2bba00b8c1c57aefc7
출처 메모	uspto-grants-2015_05