Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-Tert-butyl-5-(4-methylpiperidin-1-yl)-6-nitrobenzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-Methylpiperidine | HCID 69381 | — |
| 반응물 | 2-Tert-butyl-5-chloro-6-nitrobenzothiazole | HCID 19794202 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 2-Tert-butyl-5-(4-methylpiperidin-1-yl)-6-nitrobenzothiazole | HCID 19794189 | — |
반응 단계
A solution of 32,4 g of 2-tert-butyl-5-chloro-6-nitrobenzothiazole, (described in European patent application 85810418.5 published under No. 0175650) in 300 ml of dimethylsulphoxide, is stirred and heated at 140° for 6 hours with 12.8 g of 4-methylpiperidine and 35.8 g of anhydrous potassium carbonate, cooled and poured into water. The solid obtained is dissolved in chloroform and filtered through a silical gel column. The filtate is evaporated to give 2-tert-butyl-5-(4-methylpiperidin-1-yl)-6-nitrobenzothiazole melting at 116°-120°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246927 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-269df9c1e534472b9cb72738c8208fee |
| 출처 메모 | uspto-grants-1993_09 |