Ammonia methanol → 4-{[(1R)-1-(3-nitrophenyl)ethyl]amino}quinazoline-8-carboxamide
반응식
[N+:1]([C:4]1[CH:5]=[C:6]([C@H:10]([NH:12][C:13]2[C:22]3[C:17](=[C:18]([C:23]([O:25]C)=O)[CH:19]=[CH:20][CH:21]=3)[N:16]=[CH:15][N:14]=2)[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[NH3:27].CO>>[N+:1]([C:4]1[CH:5]=[C:6]([C@H:10]([NH:12][C:13]2[C:22]3[C:17](=[C:18]([C:23]([NH2:27])=[O:25])[CH:19]=[CH:20][CH:21]=3)[N:16]=[CH:15][N:14]=2)[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]참가 물질
3
실험 절차
A suspension of Methyl 4-{[(1R)-1-(3-nitrophenyl)ethyl]amino}quinazoline-8-carboxylate (7.26 g, 20.60 mmol) in 7 N ammonia/methanol (100 mL)
출처 및 근거
- ORD 기록
- ord-d1514dd1726b41b6989a7804cb601448
- 출처 데이터셋
- uspto-grants-2015_05
- 특허 번호
- US09040560B2
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