Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Tert-butyl-5-(4-methylpiperazin-1-yl)-6-nitrobenzothiazole → 6-Amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Tert-butyl-5-(4-methylpiperazin-1-yl)-6-nitrobenzothiazole | HCID 19794200 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-Amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole | HCID 19794176 | — |
반응 단계
A solution of 86 g of the above nitro compound in 150 ml of ethanol is hydrogenated in presence of 30 g of Raney nickel at 45°. The solution is filtered to give 6-amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole, melting at 130° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246927 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-c4b9469cd7684e858e4abf2ec83970cc |
| 출처 메모 | uspto-grants-1993_09 |