Triethylamine → 1-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylethylidene)hydrazine

HRID 579223

반응식

HRID 579223 반응식
[CH3:1][NH:2][N:3]=[C:4]([CH3:6])[CH3:5].C(N(CC)CC)C.[CH2:14]([C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[C:18]([CH2:23][CH3:24])[C:17]=1[C:25](=[O:29])[C:26](Cl)=[O:27])[CH3:15]>C(#N)C>[CH2:14]([C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[C:18]([CH2:23][CH3:24])[C:17]=1[C:25](=[O:29])[C:26]([N:2]([CH3:1])[N:3]=[C:4]([CH3:6])[CH3:5])=[O:27])[CH3:15]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 798402-Propanone, methylhydrazoneHCID 569427122-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl chloride

생성물 1

HCID 866893431-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylethylidene)hydrazine

시약·촉매·용매 1

HCID 6342Acetonitrile용매2회

반응 조건

온도
1 °C

실험 절차

To a 1000 ml volume four-necked flask, 1-methyl-2-(2-propylidene)hydrazine (17-a) (9.61 g), acetonitrile (280 ml), and triethylamine (17 ml) were added under a nitrogen atmosphere and cooled to about 1° C. To the mixture, 2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl chloride (6-a) (27.12 g) dissolved in acetonitrile (77 ml) was added dropwise over 30 minutes.

후처리

  1. additionwas added dropwise over 30 minutes

출처 및 근거

ORD 기록
ord-356a1f14b37e4426aaf3ff49f85d1f73
출처 데이터셋
uspto-grants-2015_05
특허 번호
US09040709B2

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