Acetic Acid → 2-Methoxy-4-(methylamino)-5-nitrophenol

HRID 579691노트

반응식

HRID 579691 반응식
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]2[O:9][CH2:10][O:11][C:6]2=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].C[O-].[Na+].C(O)(=O)C>CO.O>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([NH:2][CH3:1])[C:4]([N+:12]([O-:14])=[O:13])=[CH:5][C:6]=1[OH:11]

참가 물질

6

반응물 3

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13742671N-methyl-6-nitro-1,3-dioxaindan-5-amine

생성물 1

HCID 137426772-Methoxy-4-(methylamino)-5-nitrophenol

시약·촉매·용매 2

HCID 887Methanol용매2회HCID 962Water용매

실험 절차

A solution of 0.1 mol (19.6 g) of 2-methylamino-4,5-methylenedioxy-1-nitrobenzene, prepared according to Example 3, in 80 ml of a 30% strength solution of sodium methylate in methanol is brought for 15 minutes to the refluxing temperature of the methanol. The reaction medium is diluted with 500 ml of water. After the filtrate has been neutralized with acetic acid, the expected product precipitates.

후처리

  1. customthe expected product precipitates

출처 및 근거

ORD 기록
ord-9264688154a34f7aa552f22b3eac3875
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04749379

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