5-Chlorovaleryl chloride → HCID 13656413, 화합물
반응식
[NH2:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][S:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]1=2.[Cl:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22](Cl)=[O:23]>O1CCOCC1>[Cl:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([NH:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][S:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]1=2)=[O:23]참가 물질
4
실험 절차
A mixture of 8.8 g of 11-amino-6,11-dihydrodibenzo[b,e]thiepin, 6.0 g of 5-chlorovaleryl chloride and 100 ml of dioxane is heated with stirring under reflux for 15 hours. The solvent is distilled off under reduced pressure. The residue is recrystallized from ethanol to give 12.5 g of the title compound, m.p. 155°-156° C.
후처리
- temperatureis heated
- temperatureunder reflux for 15 hours
- distillationThe solvent is distilled off under reduced pressure
- customThe residue is recrystallized from ethanol
출처 및 근거
- ORD 기록
- ord-803d42ff85124d48bb7b648bf79a6341
- 출처 데이터셋
- uspto-grants-1988_06
- 특허 번호
- US04749703
반응 노트
불러오는 중…