Benzaldehyde → 1-Propanamine, 2-methyl-N-(phenylmethylene)-

HRID 579838노트

반응식

HRID 579838 반응식
[CH2:1]([NH2:5])[CH:2]([CH3:4])[CH3:3].[CH:6](=O)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C1C=CC=CC=1>[CH:6](=[N:5][CH2:1][CH:2]([CH3:4])[CH3:3])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

참가 물질

4

반응물 2

HCID 240BenzaldehydeHCID 6558Isobutylamine

생성물 1

HCID 118050671-Propanamine, 2-methyl-N-(phenylmethylene)-수율 89.4%

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

To a stirred solution of isobutylamine (49.7 ml, 500 mmol) in dry benzene (50 ml) was added benzaldehyde (50.8 ml, 500 mmol) over a period of 20 minutes. After three hours, the water layer was separated and the stirring of the benzene solution continued overnight. Again the separated water layer was discarded. The benzene layer after further dilution with dry benzene (150 ml) was dried over a minimum amount of magnesium sulfate. After concentrating the dried benzene solution, the residue was distilled in vacuo, yielding 72.1 g of compound, boiling point 46°-48° C. at 0.1 mm of Hg.

후처리

  1. customthe water layer was separated
  2. waitcontinued overnight
  3. dry with materialThe benzene layer after further dilution with dry benzene (150 ml) was dried over a minimum amount of magnesium sulfate
  4. concentrationAfter concentrating the dried benzene solution
  5. distillationthe residue was distilled in vacuo

출처 및 근거

ORD 기록
ord-ee6bd03996a4456c88fc4dbebd772638
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04749792

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