4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580083

반응식

HRID 580083 반응식
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14].Cl>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

5

반응물 2

HCID 5414-NitrobenzaldehydeHCID 22471726HCID 22471726, 화합물

생성물 1

HCID 96339p-Nitrobenzaldoxime수율 96.3%

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매2회

반응 조건

온도
30 °C

실험 절차

453 g (3 mols) of p-nitrobenzaldehyde was dissolved in 1350 ml of methanol and then, an aqueous solution of 241 g (3.3 mols) of hydrochloric acid hydroxylamine hydrochloride in 300 ml of water was added dropwise over 30 minutes while maintaining the reaction temperature at 30° C. Thereafter, stirring was effected at the same temperature for two hours and the mixture was diluted with 2000 ml of water. White crystals deposited were filtered, washed with water and dried. 480 g of p-nitrobenzaldoxime was obtained (yield, 96.5%). M.P. 128° to 131° C.

후처리

  1. filtrationWhite crystals deposited were filtered
  2. washwashed with water
  3. customdried

출처 및 근거

ORD 기록
ord-43e5868c1ad648ac86e21e30d1b2af03
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04751328

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