2-Chloro-6-hydroxybenzaldehyde → 5-Chloro-1-benzofuran-2-carboxylic acid

반응식

[Cl:1]C1C=CC=C(O)C=1C=O.F[C:12]1[CH:23]=[CH:22][C:15]2[O:16][C:17]([C:19]([OH:21])=[O:20])=[CH:18][C:14]=2[CH:13]=1.ClC1C=CC2C=C(C(O)=O)OC=2C=1>>[Cl:1][C:12]1[CH:23]=[CH:22][C:15]2[O:16][C:17]([C:19]([OH:21])=[O:20])=[CH:18][C:14]=2[CH:13]=1

참가 물질

반응물 3

HCID 5283932-Chloro-6-hydroxybenzaldehyde

HCID 109868725-Fluoro-1-benzofuran-2-carboxylic acid

HCID 137487046-Chloro-1-benzofuran-2-carboxylic acid

생성물 1

HCID 9378385-Chloro-1-benzofuran-2-carboxylic acid

실험 절차

By the same procedure, 5-fluorosalicyaldehyde and 6-chlorosalicylaldehyde are converted, respectively, to 5-fluorobenzo[b]furan-2-carboxylic acid and 6-chlorobenzo[b]furan-2-carboxylic acid.

출처 및 근거

ORD 기록: ord-c0208f5fcdde48b1a8e72f9b8b11157d
출처 데이터셋: uspto-grants-1988_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04753956

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