Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Hydroxide → 4-Amino-3-nitrobenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | 4-Fluoro-3-nitrobenzaldehyde | HCID 598129 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Amino-3-nitrobenzaldehyde | HCID 13237703 | 53% |
반응 단계
To a solution of 4-fluoro-3-nitro-benzaldehyde (570 g, 3.3 mmol) in THF (20 mL) was added NH4OH (5 mL). The reaction mixture was stirred at room temperature for 1 hour. The resulting yellow solid was collected and washed with water, dried under vacuum to give the title compound (300 mg, yield: 53%). 1H-NMR (300 MHz, DMSO-d6) δ 9.76 (s, 1H), 8.57 (d, 1H), 8.18 (br s, 2H), 7.80 (dd, 1H), 7.10 (d, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434697B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-a79753c21c134e12a38d92360c5294dc |
| 출처 메모 | uspto-grants-2016_09 |