참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzene, 2-fluoro-4-methyl-1-nitro- | HCID 67966 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | [2-(3-Fluoro-4-nitro-phenyl)-vinyl]-dimethyl-amine | HCID 91252016 | 63% |
반응 단계
A mixture of 2-fluoro-4-methyl-1-nitro-benzene (3 g, 19.3 mmol), N,N-dimethylformamide dimethylacetal (10 mL) and 3 mL of DMF (30 mL) was heated at 125° C. for 1 hour. The mixture was cooled and concentrated under reduced pressure to give a purple solid. Trituration with hexanes gave the pure title product (2.5 g, yield: 63%). MS (ESI): 211 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09434697B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_09 |
|---|
| ORD ID | ord-817877ea94764f208294308ee7121a8b |
|---|
| 출처 메모 | uspto-grants-2016_09 |
|---|
