Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl bromoacetate → ethyl N-(4-fluorophenyl)glycine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl bromoacetate | HCID 7748 | — |
| 반응물 | 4-Fluoroaniline | HCID 9731 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 18-Crown-6 | HCID 28557 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | ethyl N-(4-fluorophenyl)glycine | HCID 61998283 | — |
반응 단계
4-Fluoroaniline (5 g), potassium carbonate (3.11 g) and a catalytic amount of 18-Crown-6 were stirred together in 50 ml of ethanol. A solution of ethylbromoacetate (7.52 g) in 25 ml of ethanol was added dropwise and the reaction was heated to reflux.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246933 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-d5edec4fc25d4165a206856d008fcc0a |
| 출처 메모 | uspto-grants-1993_09 |