Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate
반응식
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][CH:3]=1.[Br:15]Br.ClC(Cl)(Cl)Cl>O>[Br:15][C:3]1[CH:4]=[CH:5][C:6]([O:13][CH3:14])=[C:7]([C:2]=1[CH3:1])[C:8]([O:10][CH2:11][CH3:12])=[O:9]참가 물질
5
실험 절차
A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87.% y) and is used without further purification.
후처리
- extractionextracted with ethyl acetate
- customThe organic phase is separated
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-b1a6c1867ea34f2692ef6cf0673d0db8
- 출처 데이터셋
- uspto-grants-1999_07
- 특허 번호
- US05922905
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