Benzaldehyde → HCID 689895, 화합물

HRID 582415노트

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HRID 582415 반응식
[C:1]([O:5][C:6]([CH3:9])([CH3:8])[CH3:7])(=[O:4])[NH:2][NH2:3].[CH:10](=O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(O)C>[C:6]([O:5][C:1]([NH:2][N:3]=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:4])([CH3:9])([CH3:8])[CH3:7]

참가 물질

4

반응물 2

HCID 240BenzaldehydeHCID 70091tert-Butyl carbazate

생성물 1

HCID 689895HCID 689895, 화합물수율 81.2%

시약·촉매·용매 1

HCID 702Ethanol용매

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온도
0 °C

실험 절차

1-((2R)-2-(N-((2E)-5-Amino-5-methylhex-2-enoyl)-N-methyl amino)-3-(2-naphthyl)propionyl-2-benzyl-4-ethylsemi-carbazide ##STR183## N'-Benzylidenehydrazinecarboxylic acid tert-butyl ester: ##STR184## To a solution of t-butyl carbazate (2.0 g, 15.1 mmol) in 99% ethanol (20 ml) was added benzaldehyde (1.6 g, 15.1 mmol) and the mixture was stirred for 30 min. Then the mixture was cooled to 0° C. and the precipitate was separated and washed with cold ethanol and dried in vacuo to give 2.7 g (81%) of N'-benzylidenehydrazinecarboxylic acid tert-butyl ester.

후처리

  1. customthe precipitate was separated
  2. washwashed with cold ethanol
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-cfbdd75e1a9c493dbc212edc87f58feb
출처 데이터셋
uspto-grants-1999_07
특허 번호
US05922770

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