참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 5-Amino-2-chlorobenzoic acid | HCID 37879 | — |
| 반응물 | Stannous chloride dihydrate | HCID 61436 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Chloro-5-hydrazinylbenzoic acid hydrochloride | HCID 16495725 | 123.1% |
반응 단계
A solution of 2.11 g of NaNO2 in 40 ml of water is added over 30 minutes to a suspension, cooled to -2° C., of 5 g of 5-amino-2-chlorobenzoic acid in 50 ml of concentrated HCl. The solution is stirred for 2 hours at -3° C. and cooled to -10° C., and a solution of 23 g of SnCl2.2H2O in 20 ml of concentrated HCl and 20 ml of water is added over 30 minutes. The mixture is stirred for one and a half hours at 0° C. and filtered, and the precipitate is dried to obtain 4 g of expected product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05925661 |
|---|
| 출처 데이터셋 | uspto-grants-1999_07 |
|---|
| ORD ID | ord-6ca3a4300596418a926de5c4fa29c061 |
|---|
| 출처 메모 | uspto-grants-1999_07 |
|---|
