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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 582779생성일: 2026년 10월 26일

Maleic Acid → 2-[5-(2,6-Dimethoxyphenyl)-1-[4-[N-methyl-N-(3-dimethylaminopropyl)carbamoyl]-2-isopropylphenyl]-3-pyrazolylcarbonylamino]-2-adamantanecarboxylic acid maleate

https://huagongshe.com/reaction/582779

반응식

참여 물질

역할이름HCID투입량
반응물Maleic AcidHCID 444266—
반응물SR142948AHCID 5311451—
용매IsopropanolHCID 3776—
생성물2-[5-(2,6-Dimethoxyphenyl)-1-[4-[N-methyl-N-(3-dimethylaminopropyl)carbamoyl]-2-isopropylphenyl]-3-pyrazolylcarbonylamino]-2-adamantanecarboxylic acid maleateHCID 7024498334.2%

반응 단계

0.1 g of the compound obtained in EXAMPLE 1' and 0.017 g of maleic acid are dissolved in the heated state in 2.3 ml of 2-propanol, and the mixture is concentrated under vacuum. The residue is dissolved in 0.3 ml of EtOH, this solution is poured into 30 ml of ether and the precipitate formed is drained. 0.04 g of the expected product is obtained, m.p.=260° C. (dec.).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05925661
출처 데이터셋uspto-grants-1999_07
ORD IDord-04bc1c6ca1d64c45a9f25db9982b6041
출처 메모uspto-grants-1999_07