Ammonium Hydroxide → HCID 21584299, 화합물

HRID 583256노트

반응식

HRID 583256 반응식
[CH2:1]1[CH:10]2[N:5]([C:6](=[O:15])[C:7]3[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=3[CH2:9]2)[CH2:4][CH2:3][CH2:2]1.[N+:16]([O-])([O-:18])=[O:17].[K+].[OH-].[NH4+]>S(=O)(=O)(O)O>[N+:16]([C:13]1[CH:12]=[CH:11][C:8]2[CH2:9][CH:10]3[N:5]([C:6](=[O:15])[C:7]=2[CH:14]=1)[CH2:4][CH2:3][CH2:2][CH2:1]3)([O-:18])=[O:17]

참가 물질

5

반응물 3

HCID 14923Ammonium HydroxideHCID 24434Potassium NitrateHCID 27527926H-Benzo[b]quinolizin-6-one, 1,2,3,4,11,11a-hexahydro-

생성물 1

HCID 21584299HCID 21584299, 화합물수율 92%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

1,3,4,6,11,11a-Hexahydro-2H-benzo[b]quinolizin-6-one (3.78 g, 18.7 mmol) was dissolved in concentrated sulfuric acid (50 ml) at 0° C., potassium nitrate (2.02 g, 20 mmol) was added and the reaction mixture was stirred overnight. The reaction mixture was poured onto ice (200 g) and was partially neutralized with concentrated ammonium hydroxide. The precipitate was collected and air-dried to give the title compound as a yellow solid (4.22 g, 92%), m.p. 137-42° C.

후처리

  1. additionThe reaction mixture was poured onto ice (200 g)
  2. customThe precipitate was collected
  3. customair-dried

출처 및 근거

ORD 기록
ord-c2d9d7ced0324aeb98d237805c14bbec
출처 데이터셋
uspto-grants-1999_07
특허 번호
US05929085

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