4-Vinylbenzoic acid → 4-Vinylbenzoyl chloride
반응식
[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][CH:4]=1)=[CH2:2].C(Cl)(=O)C([Cl:15])=O>C1C=CC=CC=1>[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:15])=[O:8])=[CH:5][CH:4]=1)=[CH2:2]참가 물질
4
실험 절차
To a clean round bottom flask with an argon atmosphere and equipped with a magnetic stir bar is added para-vinyl benzoic acid (10 g, 0.067 mole) which is suspended in benzene (25 ml). Oxalyl chloride (25 g, 0.197 mole) is added to the flask. The mixture is stirred for 8 hours and continuously flushed with a continuous stream of argon to purge the system of the gases generated during the reaction. Solvent and excess oxalyl chloride is stripped off under vacuum. Finally, the product is distilled under vacuum to yield para-vinyl benzoyl chloride. Approximately 90% of the theoretical yield is obtained.
후처리
- customTo a clean round bottom flask with an argon atmosphere and equipped with a magnetic stir bar
- customcontinuously flushed with a continuous stream of argon
- customto purge the system of the gases
- customgenerated during the reaction
- distillationFinally, the product is distilled under vacuum
출처 및 근거
- ORD 기록
- ord-401d8099b2454290a09de4fe33b1af82
- 출처 데이터셋
- uspto-grants-1999_07
- 특허 번호
- US05929173
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