Sulfadiazine → N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-2-[[2-[[4-(pyrimidin-2-ylsulfamoyl)phenyl]carbamoyl]phenyl]disulfanyl]benzamide

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This compound was prepared according to the general methods described in Example 1 using 2,2'-dithiobisbenzoyl chloride (3.0 g, 8.7 mmol) in 30 mL dichloromethane and 4-amino-N-(2-pyrimidinyl) benzenesulfonamide (5.3 g, 21.7 mmol) in 100 mL pyridine. The crude product was recrystallized from a mixture of dimethylformamide, ethanol, and water to yield 3.9 g of the title compound, mp 280° C.

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