Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-(2-Aminoethyloxy)benzoyl-2(S)-phenylsulfonylamino-beta-alanine-HCl
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | 4-[2-(N-BOC-Amino)ethyloxy]benzoyl-2(S)-phenylsulfonylamino-beta-alanine tert-butyl ester | HCID 10840664 | — |
| 생성물 | 4-(2-Aminoethyloxy)benzoyl-2(S)-phenylsulfonylamino-beta-alanine-HCl | HCID 86754335 | — |
반응 단계
A suspension of 2-3 (105 mg, 0.19 mmol) in 6N HCl (5 mL) was treated with dioxane (5 mL) to effect a homogeneous solution. After stirring for 20 h at ambient temperature, the solvents were evaporated and the resulting residue azeotroped with toluene to afford 12-1 as a colorless solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05929120 |
| 출처 데이터셋 | uspto-grants-1999_07 |
| ORD ID | ord-3545c1a839b84107a6729d4bc39d022f |
| 출처 메모 | uspto-grants-1999_07 |