Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3,4,5-Trimethoxyphenyl 6-methoxy-3-pyridinesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 3,4,5-Trimethoxyphenol | HCID 69505 | — |
| 반응물 | 6-Methoxypyridine-3-sulfonyl chloride | HCID 22344709 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3,4,5-Trimethoxyphenyl 6-methoxy-3-pyridinesulfonate | HCID 10286875 | 83.3% |
반응 단계
A solution of 2-methoxypyridine-5-sulfonylchloride (314 mg, 1.51 mmol) in dichloromethane (15 mL) was treated with triethylamine (0.63 mL) and 3,4,5-trimethoxyphenol (279 mg, 1.51 mmol), stirred for 18 hours at room temperature, diluted with ethyl acetate, washed three times with 1M Na2CO3, dried (MgSO4), filtered, and concentrated to provide 447 mg of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06924304B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-e5cf63a01e114696b9636a9a1471802b |
| 출처 메모 | uspto-grants-2005_08 |