2-Bromopropane → 1-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

HRID 584051노트

반응식

HRID 584051 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH:18](Br)([CH3:20])[CH3:19]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][N:15]([CH:18]([CH3:20])[CH3:19])[CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:7]=1

참가 물질

3

반응물 2

HCID 63582-BromopropaneHCID 223451951-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

생성물 1

HCID 223451511-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

실험 절차

Beginning with 1-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine and iso-propylbromide, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV) 306 (M+, 30), 291 (bp), 206 (25), 193 (15), 179 (20).

후처리

  1. customthe title compound was recovered by the procedure

출처 및 근거

ORD 기록
ord-53d990238b7f4cc7805985359ad9086d
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06924374B2

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