Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-(Methylsulfonyl)benzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Potassium Permanganate | HCID 516875 | — |
| 반응물 | 4-(Methylthio)benzonitrile | HCID 590960 | — |
| 반응물 | Sodium Bisulfite | HCID 23665763 | — |
| 생성물 | 4-(Methylsulfonyl)benzonitrile | HCID 519981 | 82% |
반응 단계
4-Methylsulfanyl-benzonitrile (250 mg, 1.68 mmol) was dissolved in 12 mL of HOAc. Potassium permanganate (531 mg, 3.36 mmol) was added as an aqueous solution (7-8 mL). After stirring 30 min at RT, NaHSO3 was added with stirring until the brown color of the solution disappeared. The mixture was concentrated and diluted with water. The precipitate was filtered and dried in vacuo to yield 4-methanesulfonyl-benzonitrile (250 mg, 82%) which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06924284B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-9846733ca9f24b588cde6fd012db9f92 |
| 출처 메모 | uspto-grants-2005_08 |