Triethylamine → HCID 22342905, 화합물

HRID 584169

반응식

HRID 584169 반응식
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[N:6]1[CH:11]=[CH:10][CH:9]=[C:8](/[CH:12]=[CH:13]/[CH2:14][OH:15])[CH:7]=1.C(N(CC)CC)C>ClCCl>[CH3:1][S:2]([O:15][CH2:14]/[CH:13]=[CH:12]/[C:8]1[CH:7]=[N:6][CH:11]=[CH:10][CH:9]=1)(=[O:4])=[O:3]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 5861913(2E)-3-(3-Pyridinyl)-2-propen-1-ol

생성물 1

HCID 22342905HCID 22342905, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Methane sulfonyl chloride (0.22 ml) was added to a mixture of (E)-3-(3-pyridyl)-2-propen-1-ol (0.36 g) and triethylamine (0.74 ml) in dichloromethane (5 ml) under −10° C. After being stirred at the same temperature for 0.5 hour, the reaction mixture was washed with saturated sodium bicarbonate, dried over magnesium sulfate and evaporated under reduced pressure to give (E)-3-(3-pyridyl)-2-propen-1-yl methanesulfonate.

후처리

  1. washthe reaction mixture was washed with saturated sodium bicarbonate
  2. dry with materialdried over magnesium sulfate
  3. customevaporated under reduced pressure

출처 및 근거

ORD 기록
ord-95247ec2591a44b78f54802f377e74da
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06924278B2

연결된 노트

불러오는 중…