Triisopropyl borate → 5-[1,3]Dioxolan-2-yl-2-methylphenylboronic acid

반응식

Br[C:2]1[CH:3]=[C:4]([CH:9]2[O:13][CH2:12][CH2:11][O:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].[B:14](OC(C)C)([O:19]C(C)C)[O:15]C(C)C>>[O:10]1[CH2:11][CH2:12][O:13][CH:9]1[C:4]1[CH:5]=[CH:6][C:7]([CH3:8])=[C:2]([B:14]([OH:19])[OH:15])[CH:3]=1

참가 물질

반응물 2

HCID 21531Triisopropyl borate

HCID 112419791,3-Dioxolane, 2-(3-bromo-4-methylphenyl)-

생성물 1

HCID 223456365-[1,3]Dioxolan-2-yl-2-methylphenylboronic acid

실험 절차

In a manner similar to that of Example 2(k), by reacting 11.1 g (46 mmol) of 2-(3-bromo-4-methylphenyl)[1,3]dioxolane with 12.3 ml (55 mmol) of triisopropyl borate, 6 g (88%) of product are obtained in the form of an oil.

후처리

customare obtained in the form of an oil

출처 및 근거

ORD 기록: ord-d41da316721d4ee38d4763bbf5e49684
출처 데이터셋: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06924400B2

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