Dicyclohexylamine → 2-Butyloctanoyl chloride
반응식
C1(NC2CCCCC2)CCCCC1.[CH2:14]([CH:18]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[C:19](O)=[O:20])[CH2:15][CH2:16][CH3:17].S(Cl)([Cl:30])=O>ClCCl.C(OCC)C>[CH2:14]([CH:18]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[C:19]([Cl:30])=[O:20])[CH2:15][CH2:16][CH3:17]참가 물질
6
실험 절차
500 μl (2.5 mmol) of dicyclohexylamine are added to 500 mg (2.5 mmol) of 2-butyloctanoic acid placed in 5 ml of dichloromethane, and the solution is stirred at room temperature for minutes. 200 μl (2.5 mmol) of thionyl chloride are then added and this mixture is stirred at room temperature for 2 hours. The reaction is diluted with ethyl ether. The precipitate is filtered off and rinsed with ethyl ether. Concentration of the filtrate gives the 2-butyloctanoyl chloride.
후처리
- stirringthis mixture is stirred at room temperature for 2 hours
- filtrationThe precipitate is filtered off
- washrinsed with ethyl ether
출처 및 근거
- ORD 기록
- ord-9601ec8bb4c6491c9bb1c2911ace1e2b
- 출처 데이터셋
- uspto-grants-2005_08
- 특허 번호
- US06927228B2
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