Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Toluidine → 1-(2-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Toluidine | HCID 7242 | — |
| 반응물 | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(2-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid | HCID 4405457 | 91% |
반응 단계
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g, 1.47 mmol) and o-toluidine (0.470 mL; 4.41 mmol) in ethanol (3 mL). 2-oxo-1-o-tolylpyrrolidine-3-carboxylic acid 0.292 g (91%) was obtained as a white film.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434722B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-53d1152f05f74e8bad11f9b10c4d6e93 |
| 출처 메모 | uspto-grants-2016_09 |