Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Difluoroaniline → 1-(2,6-Difluorophenyl)-2-oxopyrrolidine-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Difluoroaniline | HCID 79647 | — |
| 반응물 | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(2,6-Difluorophenyl)-2-oxopyrrolidine-3-carboxylic acid | HCID 24275252 | 46% |
반응 단계
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g; 1.45 mmol) and 2,6-difluoroaniline (0.575 g; 4.36 mmol) in ethanol (3 mL). 1-(2,6-difluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 0.161 g (46%) was obtained as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434722B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-403f6f210d654a6da0ce8deb6b58b2e6 |
| 출처 메모 | uspto-grants-2016_09 |