Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Nitrate → 5-Bromo-8-nitroisoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Nitrate | HCID 24434 | — |
| 반응물 | 5-Bromoisoquinoline | HCID 736487 | — |
| 용매 | Ammonium Hydroxide | HCID 14923 | — |
| 생성물 | 5-Bromo-8-nitroisoquinoline | HCID 816983 | — |
반응 단계
The diethyl ether solution from Example 57A was treated with potassium nitrate (10.1 g, 100 mmol). After stirring for one hour, The mixture was poured onto ice and neutralized with concentrated ammonium hydroxide (˜300 ml). The crude product was collected by filtration, dried, and recrystalization from methanol to provide the title compound (8.83 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06933311B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-8378bd2b8abd47ef93fa966ae2e38faa |
| 출처 메모 | uspto-grants-2005_08 |