Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Dichlorophenethylamine → N-[2-(2,4-dichlorophenyl)ethyl]-N'-1H-indol-4-ylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Dichlorophenethylamine | HCID 142938 | — |
| 반응물 | 4-isocyanato-1H-indole | HCID 22032644 | — |
| 생성물 | N-[2-(2,4-dichlorophenyl)ethyl]-N'-1H-indol-4-ylurea | HCID 9975018 | — |
반응 단계
2-(2,4-Dichlorophenyl)ethylamine (0.21 g, 1.1 mmol) and the product of Example 80A (0.16 g, 1. mmol) were treated as described in Example 80B to provide the title compound. mp 170° C.; 1H NMR (300 MHz, DMSO-d6) δ 2.90 (m, 2H), 3.31 (m, 2H), 6.47 (m, 2H), 6.93 (m, 2H), 7.23 (m, 1H), 7.40 (m, 2H), 7.60 (m, 2H), 8.15 (s, 1H), 11.02 (s, 1H). MS (DCI+) m/z 347 (M+H). Anal. Calcd. for C17H15N3Cl20: C, 58.63; H, 4.34; N, 12.07. Found: C, 58.49; H, 4.49; N, 12.38.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06933311B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-f0e02111fadd487abf37f38ced233cc6 |
| 출처 메모 | uspto-grants-2005_08 |