Thionyl Chloride → 2-(4-Chlorophenyl)-2-methylpropanoyl chloride

HRID 586056노트

반응식

HRID 586056 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9](O)=[O:10])=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([Cl:16])=[O:10])=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 804062-(4-Chlorophenyl)-2-methylpropionic acid

생성물 1

HCID 135368632-(4-Chlorophenyl)-2-methylpropanoyl chloride

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

2-(4-Chlorophenyl)-2-methylpropanoic acid (3.85 g, 19.4 mmol) in toluene (5 mL) and thionyl chloride (5.00 g, 3.1 mL) was heated at 80° C. for 2 hours. The mixture was cooled and concentrated under reduced pressure to provide the title compound.

후처리

  1. temperatureThe mixture was cooled
  2. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-e1369f3beefb40839e681d647c5c4b1a
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06933311B2

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