3,4,5-Trimethoxyphenol → 2-(4-Bromophenyl)-5,7-dimethyl-4-(3,4,5-trimethoxyphenoxy)imidazo[5,1-f][1,2,4]triazine

HRID 586154

반응식

HRID 586154 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[C:12](N3C=NC=N3)[C:11]3=[C:19]([CH3:23])[N:20]=[C:21]([CH3:22])[N:10]3[N:9]=2)=[CH:4][CH:3]=1.[CH3:24][O:25][C:26]1[CH:27]=[C:28]([OH:36])[CH:29]=[C:30]([O:34][CH3:35])[C:31]=1[O:32][CH3:33]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:13]=[C:12]([O:36][C:28]3[CH:29]=[C:30]([O:34][CH3:35])[C:31]([O:32][CH3:33])=[C:26]([O:25][CH3:24])[CH:27]=3)[C:11]3=[C:19]([CH3:23])[N:20]=[C:21]([CH3:22])[N:10]3[N:9]=2)=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 695053,4,5-TrimethoxyphenolHCID 223296222-(4-Bromophenyl)-5,7-dimethyl-4-(1H-1,2,4-triazol-1-yl)imidazo[5,1-f][1,2,4]triazine

생성물 1

HCID 120957012-(4-Bromophenyl)-5,7-dimethyl-4-(3,4,5-trimethoxyphenoxy)imidazo[5,1-f][1,2,4]triazine

실험 절차

Preparation analogously to Example 22 from Example 50A (50 mg, 0.14 mmol) and 3,4,5-trimethoxyphenol (50 mg, 0.29 mmol).

출처 및 근거

ORD 기록
ord-747eb775348d4cb0b594695b1fc0f1cd
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06936609B2

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