참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Acetyl-4-(2-hydroxyethyl)piperazine | HCID 4739629 | — |
반응 단계
To a solution of 1-(2-hydroxyethyl)piperazine (5.5 ml; 42.3 mmol) in toluene (50 ml) was added acetic anhydride (4.0 ml; 42.4 mmol). The mixture was heated to 80° C. overnight. The solvent was removed under reduced pressure and the residue was washed several times with a mixture of diethyl ether and petroleum ether (1:1 v/v) to leave 6q1 as an oil (5.2 g; 72%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06936613B2 |
|---|
| 출처 데이터셋 | uspto-grants-2005_08 |
|---|
| ORD ID | ord-42f75320e462433eba0a700c6284fe01 |
|---|
| 출처 메모 | uspto-grants-2005_08 |
|---|
