Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Chloro-2-methylphenyl isothiocyanate → 1-(5-Chloro-2-methyl-phenyl)-3-(4-methyl-oxazol-2-yl)-thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Chloro-2-methylphenyl isothiocyanate | HCID 29519 | — |
| 반응물 | 4-Methyloxazol-2-amine | HCID 535824 | — |
| 생성물 | 1-(5-Chloro-2-methyl-phenyl)-3-(4-methyl-oxazol-2-yl)-thiourea | HCID 9921815 | 54.1% |
반응 단계
Prepared using Method A from 10.0 g (54.5 mmol) of 5-chloro-2-methyl-phenyl isothiocyanate and 5.39 g (55 mmol) of 4-methyl-2-amino-oxazole to give 8.3 g of title compound as a yellow solid, m.p. 207-208° C. An additional crop (4.8 g, m.p. 207-208° C.) was obtained from the mother liquor (86% combined yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06936630B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-44e731206ffe4858bf931064cf3976e5 |
| 출처 메모 | uspto-grants-2005_08 |