Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine → (R)-3-[(4-(2-((Pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine | HCID 853151 | — |
| 반응물 | rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide | HCID 60197106 | — |
| 반응물 | 3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide | HCID 86679822 | — |
| 생성물 | (R)-3-[(4-(2-((Pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide | HCID 60197503 | — |
반응 단계
B31 was prepared following the procedure reported for B4 using A1 and (R)-2-((pyrrolidin-1-yl)methyl)pyrrolidine. It was obtained as a white crystalline solid; yield: 65 mg (17%). MS (ES) C19H27N7O2S requires: 417. found: 418 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09226929B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-5623d10c54154f13b44b8c89c7aaefce |
| 출처 메모 | uspto-grants-2016_01 |