5-Amino-1,2,3,4-tetrahydroisoquinoline → 3-[(4-(5-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

HRID 587173

반응식

HRID 587173 반응식
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:10]=[C:11]([CH2:15][S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][CH:14]=2)[N:3]=1.[NH2:20][C:21]1[CH:30]=[CH:29][CH:28]=[C:27]2[C:22]=1[CH2:23][CH2:24][NH:25][CH2:26]2>>[NH2:20][C:21]1[CH:30]=[CH:29][CH:28]=[C:27]2[C:22]=1[CH2:23][CH2:24][N:25]([C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:10]=[C:11]([CH2:15][S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][CH:14]=3)[N:3]=1)[CH2:26]2

참가 물질

3

반응물 2

HCID 162174995-Amino-1,2,3,4-tetrahydroisoquinolineHCID 866798223-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

생성물 1

HCID 601977003-[(4-(5-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

실험 절차

B41 was prepared following the general procedure reported for B10 using A1 and 5-amino-1,2,3,4-tetrahydroisoquinoline; yield: 61.5 mg (15%), pale yellow solid. MS (ES) C19H21N7O2S requires: 411. found: 412 (M+H)+.

후처리

  1. customB41 was prepared

출처 및 근거

ORD 기록
ord-a7fd5636d61e48be8ed04ea6bc4f4495
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09226929B2

연결된 노트

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