HCID 58577265, 화합물 → 3-N-methylpyridine-2,3-diamine
반응식
[CH2:1]([N:8](C)[C:9]1[C:10]([N+:15]([O-])=O)=[N:11][CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>CCO.[Pd]>[CH3:1][NH:8][C:9]1[C:10]([NH2:15])=[N:11][CH:12]=[CH:13][CH:14]=1참가 물질
4
실험 절차
A mixture of N-benzyl-N-methyl-2-nitropyridin-3-amine (2.6 g) and 10% Pd—C (0.569 g) in EtOH (50 mL) was hydrogenated under balloon pressure at room temperature over weekend. The catalyst was removed by filtration and the filtrate was concentrated in vacuo to give N3-methylpyridine-2,3-diamine (1.14 g) as pale yellow oil.
후처리
- waitwas hydrogenated under balloon pressure at room temperature over weekend
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated in vacuo
출처 및 근거
- ORD 기록
- ord-5f5b2d67b8434796a33c7e1d471a6136
- 출처 데이터셋
- uspto-grants-2016_01
- 특허 번호
- US09226921B2
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