Nitric Acid → HCID 90410240, 화합물

HRID 589131노트

반응식

HRID 589131 반응식
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][C:3]=1[OH:12].O.[N+:14]([O-])([OH:16])=[O:15]>C(Cl)Cl>[Br:1][C:2]1[C:3]([OH:12])=[C:4]([N+:14]([O-:16])=[O:15])[C:5]([N+:9]([O-:11])=[O:10])=[C:6]([F:8])[CH:7]=1

참가 물질

5

반응물 3

HCID 944Nitric AcidHCID 962WaterHCID 132681792-Bromo-4-fluoro-5-nitrophenol

생성물 1

HCID 90410240HCID 90410240, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

To a solution of 2-bromo-4-fluoro-5-nitrophenol (4.0 g, 17 mmol) in methylene chloride (29.5 mL), 2.0 M nitric acid in DCM (25 mL) was added and the mixture was stirred for 15 min at room temperature. The mixture was poured over cold water and extracted with methylene chloride to give the product.

후처리

  1. extractionextracted with methylene chloride
  2. customto give the product

출처 및 근거

ORD 기록
ord-7fcf471009b9404c90fdba0c7e9bf2ee
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09227985B2

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