Trifluoroacetic acid → HCID 178527493, 화합물
반응식
[O:1]1[CH:5]=[CH:4][C:3]([C:6]2[S:10][C:9]([S:11](Cl)(=[O:13])=[O:12])=[CH:8][CH:7]=2)=[N:2]1.[NH2:15][C:16]1[CH:17]=[C:18]([C:22]2[NH:26][N:25]=[N:24][N:23]=2)[CH:19]=[CH:20][CH:21]=1.C(O)(C(F)(F)F)=O>O>[O:1]1[CH:5]=[CH:4][C:3]([C:6]2[S:10][C:9]([S:11]([NH:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([C:22]4[NH:26][N:25]=[N:24][N:23]=4)[CH:17]=3)(=[O:13])=[O:12])=[CH:8][CH:7]=2)=[N:2]1참가 물질
5
실험 절차
The product was prepared according to General Procedure 1, described in Example 1, with 5-isoxazol-3-ylthiophene-2-sulfonyl chloride (13.7 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol) and with a slightly modified purification method using 0.1% TFA in water as buffet. The title compound was obtained in 54% yield (11.1 mg). MS (ESI+) calcd mass for C14H10N6O3S2 374.025580, found 374.025400.