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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 5900생성일: 2026년 10월 23일

4-Methoxy-3-methylbenzyl chloride → (RS)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-[(4-methoxy-3-methylphenyl)methoxy]-3-isoquinolinecarboxylic acid, ethyl ester

https://huagongshe.com/ko/reaction/5900

반응식

참여 물질

역할이름HCID투입량
반응물4-Methoxy-3-methylbenzyl chlorideHCID 143742—
반응물(RS)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-5-hydroxy-6-methoxy-3-isoquinolinecarboxylic acid, ethyl esterHCID 15296729—
생성물(RS)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-[(4-methoxy-3-methylphenyl)methoxy]-3-isoquinolinecarboxylic acid, ethyl esterHCID 15230314—

반응 단계

This compound is prepared from the phenol derivative of Example 31 and 4-methoxy-3-methyl benzyl chloride by a procedure similar to that in Example 32. The product is purified by silica gel chromatography; tlc (1:1 ethyl-acetate/hexane), one spot, Rf 0.7.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05246943
출처 데이터셋uspto-grants-1993_09
ORD IDord-5863e731e9c84c6190da1db07ffc1880
출처 메모uspto-grants-1993_09