Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclohexylamine → HCID 42614802, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclohexylamine | HCID 7965 | — |
| 반응물 | 3-Bromo-1-indanone | HCID 11745912 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | HCID 42614802 | HCID 42614802 | 84% |
반응 단계
3-Bromo-2,3-dihydro-1H-inden-1-one (100 mg, 475 μmol) and cyclohexylamine (94 mg, 951 μmol) were dissolved in 2 mL of dry benzene and stirred under N2 until precipitation ceased (˜15 min) The cyclohexylamine.HBr was removed by filtration. The filtrate was applied to a flash SiO2 column that was developed with 8:1 hexanes-EtOAc to give the title compound as a clear oil (91 mg, 84% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09439877B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-53548c7e825e4ed685f012ad3877349d |
| 출처 메모 | uspto-grants-2016_09 |