2-(Cyclopentyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → HCID 178494007, 화합물

반응식

[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].C1(OC2NC(N)=C3C(N=2)=NC(OC)=N3)CCC1.[CH:25]1([O:30][C:31]2[N:39]=[C:38]3[C:34]([N:35]=[C:36]([O:46][CH3:47])[N:37]3C3CCCCO3)=[C:33]([NH2:48])[N:32]=2)[CH2:29][CH2:28][CH2:27][CH2:26]1>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH:25]1([O:30][C:31]2[NH:32][C:33]([NH2:48])=[C:34]3[C:38]([N:39]=2)=[N:37][C:36]([O:46][CH3:47])=[N:35]3)[CH2:26][CH2:27][CH2:28][CH2:29]1

참가 물질

반응물 2

HCID 592525592-(Cyclopentyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

HCID 178494005HCID 178494005, 화합물

생성물 1

HCID 178494007HCID 178494007, 화합물

실험 절차

Prepared similarly to Intermediate 58 from 2-(cyclopentyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

출처 및 근거

ORD 기록: ord-32f245d8dd1e43c482c7da87aca6e97f
출처 데이터셋: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09233962B2

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