2-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → HCID 178494008, 화합물

반응식

[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].C1(OC2NC(N)=C3C(N=2)=NC(OC)=N3)CCC1.[CH:25]1([O:31][C:32]2[N:40]=[C:39]3[C:35]([N:36]=[C:37]([O:47][CH3:48])[N:38]3C3CCCCO3)=[C:34]([NH2:49])[N:33]=2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH:25]1([O:31][C:32]2[NH:33][C:34]([NH2:49])=[C:35]3[C:39]([N:40]=2)=[N:38][C:37]([O:47][CH3:48])=[N:36]3)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]1

참가 물질

반응물 2

HCID 592526492-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

HCID 178494005HCID 178494005, 화합물

생성물 1

HCID 178494008HCID 178494008, 화합물

실험 절차

Prepared similarly to Intermediate 58 from 2-(cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

출처 및 근거

ORD 기록: ord-a81946ffd0bf4a91bc4015d2bb7f612f
출처 데이터셋: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09233962B2

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