Methyl 3-amino-2-methylpropanoate hydrochloride → methyl trans-3-(aminomethyl)cyclobutane-1-carboxylate hydrochloride

HRID 590579

반응식

HRID 590579 반응식
[ClH:1].N[CH2:3][CH:4]([CH3:9])[C:5]([O:7][CH3:8])=[O:6].[NH2:10][CH2:11][CH:12]1CC(C(O)=O)C1>>[ClH:1].[NH2:10][CH2:11][CH:12]1[CH2:9][CH:4]([C:5]([O:7][CH3:8])=[O:6])[CH2:3]1

참가 물질

3

반응물 2

HCID 13063725Methyl 3-amino-2-methylpropanoate hydrochlorideHCID 585579013-(Aminomethyl)cyclobutanecarboxylic acid

생성물 1

HCID 86222900methyl trans-3-(aminomethyl)cyclobutane-1-carboxylate hydrochloride

실험 절차

Compound 81-B was prepared in analogy to compound W in Example 20 by using 3-(aminomethyl)cyclobutanecarboxylic acid (PharmaBlock (Nanjing) R&D Co. Ltd, CAS: 1310729-95-3) instead of DL-3-aminoisobutyric acid.

출처 및 근거

ORD 기록
ord-507c8b89e31741bbb337bddb82b33a5c
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09233978B2

연결된 노트

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