2-Chloronicotinoyl chloride → 2-Chloro-N-[3-[[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)phenyl]carbamoyl]phenyl]pyridine-3-carboxamide

HRID 590933노트

반응식

HRID 590933 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:29]=[CH:30][CH:31]=1)[C:5]([NH:7][C:8]1[C:13]([C:14]([F:17])([F:16])[F:15])=[CH:12][C:11]([C:18]([F:27])([C:23]([F:26])([F:25])[F:24])[C:19]([F:22])([F:21])[F:20])=[CH:10][C:9]=1[I:28])=[O:6].[Cl:32][C:33]1[N:41]=[CH:40][CH:39]=[CH:38][C:34]=1[C:35](Cl)=[O:36]>>[Cl:32][C:33]1[N:41]=[CH:40][CH:39]=[CH:38][C:34]=1[C:35]([NH:1][C:2]1[CH:31]=[CH:30][CH:29]=[C:4]([C:5](=[O:6])[NH:7][C:8]2[C:13]([C:14]([F:16])([F:17])[F:15])=[CH:12][C:11]([C:18]([F:27])([C:19]([F:20])([F:21])[F:22])[C:23]([F:24])([F:25])[F:26])=[CH:10][C:9]=2[I:28])[CH:3]=1)=[O:36]

참가 물질

3

반응물 2

HCID 27745412-Chloronicotinoyl chlorideHCID 86656694HCID 86656694, 화합물

생성물 1

HCID 866566932-Chloro-N-[3-[[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)phenyl]carbamoyl]phenyl]pyridine-3-carboxamide

실험 절차

According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide and 2-chloronicotinoylchloride.

출처 및 근거

ORD 기록
ord-3799e071d822427a9458078df46e303f
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09237745B2

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