참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 8-Chloro-4-(chloromethyl)-7-hydroxy-2H-chromen-2-one | HCID 89767929 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | (7-Chloro-6-hydroxy-1-benzofuran-3-yl)acetic acid | HCID 89767735 | — |
반응 단계
A mixture of 1N NaOH (56.7 mL) and 8-chloro-4-(chloromethyl)-7-hydroxy-2H-chromen-2-one (2.78 g) was stirred at 100° C. for 1 h. After cooling, the reaction mixture was acidified with 6N HCl (10 mL). The precipitate was collected by filtration to give the title compound (1.65 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09238639B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_01 |
|---|
| ORD ID | ord-9cb8e4a309144364acb0d39132346473 |
|---|
| 출처 메모 | uspto-grants-2016_01 |
|---|
