Formaldehyde → 3-(Hydroxymethyl)benzoselenazolinone

HRID 5918노트

반응식

HRID 5918 반응식
[Se:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH2:10]=[O:11].C[OH:13]>O>[OH:11][CH2:10][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[Se:1](=[O:13])[CH2:2]1

참가 물질

5

반응물 3

HCID 712FormaldehydeHCID 887MethanolHCID 136087Benzoselenazole

생성물 1

HCID 867472283-(Hydroxymethyl)benzoselenazolinone

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
40 °C

실험 절차

2 grams (0.01 mol) of benzoselenazoline, 2 cm3 (0.02 mol) of aqueous formaldehyde solution and 2 cm3 of methanol are introduced into a ground-necked flask. The mixture is brought to reflux two hours. After cooling to 40° C. 20 cm3 of water are added. The mixture is allowed to cool and the product is drained, washed with water, dried and recrystallized in cyclohexane.

후처리

  1. temperatureto reflux two hours
  2. temperatureto cool
  3. washwashed with water
  4. customdried
  5. customrecrystallized in cyclohexane

출처 및 근거

ORD 기록
ord-5d28e8e0676841e598914b8d0977a4cb
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05246951

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