4-Formylbenzoic acid → Ethyl 2-(4-formylbenzamido)-3-hydroxypropanoate

HRID 592071

반응식

HRID 592071 반응식
[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=1)=[O:2].[NH2:12][CH:13]([CH2:19][OH:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15]>>[CH:1]([C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:12][CH:13]([CH2:19][OH:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15])=[O:9])=[CH:10][CH:11]=1)=[O:2]

참가 물질

3

반응물 2

HCID 120884-Formylbenzoic acidHCID 410488Ethyl 2-amino-3-hydroxypropanoate

생성물 1

HCID 89725943Ethyl 2-(4-formylbenzamido)-3-hydroxypropanoate수율 34%

실험 절차

In an analogous manner to 39, 4-formyl benzoic acid (24) (1.0 g, 6.66 mmol) and ethyl 2-amino-3-hydroxypropanoate (975 mg, 7.33 mmol) were reacted to yield 600 mg (34%) of 41 as an off-white sticky solid.

출처 및 근거

ORD 기록
ord-e422a4522b1845cb85bf71cc7875e3ee
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09238656B2

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