Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus pentachloride → 2-chloro-6-fluoro-N-(4-iodophenyl)benzenecarbohydrazonoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus pentachloride | HCID 24819 | — |
| 반응물 | N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-4-iodoaniline | HCID 90020166 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 2-chloro-6-fluoro-N-(4-iodophenyl)benzenecarbohydrazonoyl chloride | HCID 131733234 | 76.4% |
반응 단계
The title compound was prepared according to the procedure described in step-2 of Intermediate-1 using (1E)-1-(2-chloro-6-fluorobenzylidene)-2-(4-iodophenyl)hydrazine (1.2 g, 3.20 mmol), PCl5 (0.990 g, 4.8 mmol) and benzene (20 mL) to afford 1.0 g of desired product. 1H NMR. (300 MHz, DMSO d6): δ 7.00 (d, J=8.7 Hz, 2H), 7.41 (d, J=8.7 Hz, 1H), 7.48-7.60 (m, 4H), 10.22 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09439890B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-96078c6f0c624753b20010b26f0d8960 |
| 출처 메모 | uspto-grants-2016_09 |